New Research on Alpha Lipoic Acid and Acetyl-L-Carnitine Demonstrates Benefits of Supplementation
Two new studies demonstrate the benefits of supplementing with two lesser-known dietary supplements. The first shows that alpha lipoic acid helps to ward off diabetes; and the second that acetyl-l-carnitine preserves cognitive function.
Alpha Lipoic Acid Instructs Cells to Efficiently Burn Glucose and Utilize Insulin
Diabetes is a devastating disease that results from an inability to properly metabolize glucose resulting from poor insulin function. Researchers writing in the Journal of Clinical Biochemistry and Nutrition found that the naturally occurring cellular antioxidant, alpha lipoic acid, has the ability to correct abnormal insulin signaling and resistance that are known to promote disease development.
Alpha lipoic acid is shown to rejuvenate energy production in the critical mitochondria and enhance the metabolism of sugars and carbohydrates to restore proper insulin activity. Most health-minded individuals will need to supplement with the biologically active “R” form of this critical antioxidant to effectively thwart metabolic disease and diabetes progression.
Alpha lipoic acid instructs our body’s trillions of cells to effectively burn glucose to be used as a fuel for metabolism and energy production. The result of this study demonstrates that the co-factor compound provides a critical link between the antioxidant status within a cell and normal insulin function. When insulin becomes resistant or ineffective due to the stress of continually high levels of blood glucose, metabolism suffers and diabetes is the end result.
Researchers found that r-alpha lipoic acid (100 mg daily) influences cellular antioxidant nutrients and enzymes. The compound was shown to have a profound influence on these critical protective structures so a perfectly efficient balance was restored that allowed them to perform optimally. As a result, proper gene signaling was restored and insulin and glucose metabolism improved. The study was the first to show that insulin regulation in a cell is closely controlled by antioxidant status, and antioxidant deterioration through poor diet and lifestyle trigger metabolic syndrome and diabetes. Alpha lipoic acid helps to restore cellular antioxidant synergy and can stave off diabetes.
Acetyl-L-Carnitine Prevents Tau Brain Tangles to Improve Memory
In addition to the amazing health benefits experienced by people supplementing with alpha lipoic acid, another naturally occurring nutrient is showing the ability to boost mood, improve cognitive function and help retain memory loss as we age. Researchers writing in the Journal Neurochemistry document the precise mechanism that acetyl-l-carnitine (500 mg, twice daily) exhibits to help prevent the formation of brain tangles that are the hallmark of Alzheimer’s disease.
Scientists found that mice supplemented with acetyl-l-carnitine for a period of two weeks protects against the formation of the tau protein tangles that are a hallmark in the development of the memory-robbing form of dementia. While tau proteins are a normal part of nerve cell construction, they are known to accumulate in a hyperactive fashion that can result in cognitive decline and memory loss. Acetyl-l carnitine helps tau proteins behave properly by interceding at the gene and molecular level to prevent dementia and memory decline.
Nature has bestowed us with a multitude of natural compounds that are particularly effective in promoting human health. Alpha lipoic acid and acetyl-l-carnitine are shown to help prevent metabolic dysfunction, diabetes and loss of cognition. Following a natural diet filled with fresh organic vegetables and fruits along with regular physical activity will help to restore youthful levels of these two super-nutrients. Some health-conscious adults may want to supplement to ensure optimal cellular saturation and disease risk reduction.
John Phillip is a diet, health and nutrition researcher and writer with a passion for understanding weight loss challenges and encouraging health modification through natural diet, lifestyle and targeted supplementation. John’s passion is to research and write about the cutting edge alternative health technologies that affect our lives.
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